Cayman Chemical ANTIBODY TK05 500ug
An LTC4 synthase inhibitor (IC50 = 95 nM); selective for LTC4 synthase over mPGES-1, GST2, and 5-LO at 10 µM; inhibits LTC4 synthase in Mono-Mac-6 cells and isolated human eosinophils, monocytes, and platelets but not cord blood-derived mast cells at 1 µM; prevents zymosan A-induced increases in peritoneal fluid levels of LTE4 and LTB4 in mice at 0.12 and 6 mg/kg